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Pharma/Biopharma

Latin American technician working at the laboratory analyzing blood samples

Overcoming Batch-to-Batch Variation in Viral Vector Manufacturing

by Andy Tay, PhD

Process and product consistency is key to regulatory approval and therapeutic outcomes

3D CG rendered image of scientifically accurate Adeno-Associated Virus (AAV) Capsid Structure based on PDB : 1LP3 (ribbon style)

Optimizing Capsid Separation with Anion Exchange Chromatography

by Brandoch Cook, PhD

Precision in Medical Dosing: The Critical Role of Accurate Balances in Modern Infusion Pump Technology

by Sartorius

Computer-generated image of a strand of RNA in purples, blues, and pale yellow

A Better Way to Make RNA Drugs

by Wyss Institute for Biologically Inspired Engineering

New enzymatic synthesis method expands RNA therapeutic capabilities while eliminating toxic byproducts

cartoon illustration of a red haired female doctor or researcher sitting on top of a giant orange and yellow pill capsule while working on a computer, surrounded by various science and medication iconography including pill bottles, a microscope, test tubes, and molecules, all on a teal background

New Derivative Synthesis Method for Development of Antimicrobial Drugs

by Hokkaido University

Comprehensive and efficient method for screening drug candidates could advance the fight against drug-resistant bacteria

a 3D rendering of red blood cells and the malaria parasite plasmodium, with green tubes representing the plasmodium and infected red blood cells containing yellow dots, with healthy red blood cells in the periphery, all on a dark grey background

Developing a New Malaria Treatment That Aims to Protect from the Disease

by SRI International

The injectable formulation is affordable, easily administered, and could potentially provide months of protection

a photo of multiple pill bottles and containers laying flat in a line on a peach colored surface with various shapes, sizes, and styles of pills spilling out of them

New Study Showcases Promising Celiac Disease Drug

by Tampere University

This new research offers strong evidence that we may be getting close to the first successful drug for celiac disease

Moving Objects with Sound

by Ecole Polytechnique Federale de Lausanne

Researchers direct floating objects through an obstacle course with soundwaves

Man with sleep apnea sleeping with a mask over his mouth

Diabetes Drug Shows Promise as a Therapy for a Sleep-Related Disorder

by University of California - San Diego

Advanced study of the drug tirzepatide finds it could be an effective treatment for obstructive sleep apnea

papercut-style illustration of the human digestive system in brown containing green, blue, yellow, and white bacteria of various shapes, all on a blue background

Towards Creating an Ingestible 'Microbiome Sampling Pill'

by Tufts University

The device has now cleared preclinical characterization

a 3d model of replication-transcription complex showing the following elements on a dark blue background: orange: RNA primer; red: RNA template; light blue: proofreading riboexonuclease; mid blue: helicase; dark blue: RNA directed RNA polymerase; violet: non structural proteins

Improving Enzymes with an Algorithm

by Trinity College Dublin

The algorithm flags where mutations could be introduced for optimal results

A Two-Step Process for Better Purification of Plasmids

by Cytiva

With ever-increasing demand for biopharmaceuticals, viral vector production still faces purification challenges

Improve AAV Product Recovery for Gene Therapy with Anion Exchange Polishing

by Cytiva

Avoid low full capsid yields with a novel, industry-verified polishing procedure

Effective AAV Processing Advances Gene Therapy Prospects

by Cytiva

Recent improvements make AAV scale-up feasible for clinical applications

illustration of molecules made of spheres connected by lines outlined in blue on a dark background with pink squares and dots in a grid, digital computation inspired, plus various numbers scattered throughout the background

New Algorithm Identifies High-Potential Molecules for Developing New Medicine

by Massachusetts Institute of Technology,Adam Zewe

Dubbed SPARROW, the system minimizes cost while maximizing candidate success likelihood

a man in blue scrubs reaches out to touch a hologram of a human heart showing healthy sinus rhythm

AI Accurately Screens for Clinical Trial Eligibility

by Mass General Brigham

With proper safeguards, AI can increase efficiency

Pills spilling out of a medicine container

New Way of Making Cyclic Peptides May Quicken Antibiotic Discovery

by King's College London

The new approach takes only minutes versus the days or hours it typically does

teal spirals filled with multicolored balls representing proteins made of amino acid chains, on a dark blue background

New Protein Study May Lead to New Antibiotics

by Massachusetts Institute of Technology,Anne Trafton

The water-soluble enzyme variant could quicken drug screening

glowing blue pill capsule sitting on a black circuit board with blue glowing circuits

Largest-Ever Antibiotic Discovery Project Uncovers Potential Cures

by Penn Medicine

Researchers use AI to trawl "microbial dark matter"

White moisture bubble helix on clear blue background with pure droplets

Gene Therapy Trial Shows Restored Hearing, Speech in Children Born Deaf

by Mass Eye and Ear

The therapy showed improvements over previous trial, such as sound source localization

Blue and white pills falling onto a light blue table with light blue background

Existing Drug May Also Treat Rare Genetic Disorder

by National Institutes of Health

Researchers find that an autoimmune disease drug alleviated symptoms of APS-1

Female scientist uses the Plas-Labs glovebox

Custom Fit: Future-Proofing Pharma with Precision Containment

by Plas-Labs

Discover how leading pharmaceutical companies leverage bespoke solutions to optimize modern manufacturing processes

Protein Discovery Advances Metabolic Disease Treatment

by University of Saskatchewan

Researchers identify peptide NLP as a potential treatment for lowering lipid levels